Assignment Example | Topics and Well Written Essays - 250 words - 117

Assignment Example Possibly, the decrease in MMP-2 in the presence of interfering mutated Ras resulted to the observed decrease in the amount of invaded cells. B) Based on figure b, MMP-2 signal is very apparent when the mutated Ras, N17Ras, is absent. On the other hand, MMP-2 signal is decreased in the presence of N17Ras. And since in the next figure the absence of N17Ras was shown to increase the number of invaded cells per field, then it is highly likely that invasion can be attributed to the presence of MMP-2, which is Ras-dependent. Again, as mentioned in part A, N17Ras competes with the wild-type Ras in the latter’s interaction with the factors that lead to the upregulation of MMP-2 (Kin et al. 55) These findings were determined using gelatin zymogram assay, as well as in vitro invasion and transwell migration assays. Particularly, gelatin zymogram assay determines the presence or absence of gelatinolytic activity of the conditioned media. This assay takes advantage of the inherent gelatinolytic activity of MMP-2 to determine the molecules presence or absence. Thus, liquidation of gelatin predicts the presence of MMP-2 (Kin et al.

Homework Research Paper Example | Topics and Well Written Essays - 1000 words

Homework - Research Paper Example The usability of a system also determines its effectiveness, satisfaction, and efficiency. The effectiveness of a system refers to the accuracy with which specific objectives can be achieved. The efficiency of a system refers to various resources and their accuracy for the system. The satisfaction of a system includes characteristics of users, tasks, and the overall organization. The context of use is also an important characteristic of the system. The context of the system determines the characteristics of the users, tasks, and physical environment (Sauro & Kindlund, 2005). The second important quality characteristic of ISO 9126 System is reliability. The reliability of a system determines the perceptions of users regarding the reliability. The reliability of a system is ensured through various measures (Sauro & Kindlund, 2005). Some of these measures include frequency of system failure, presence of bugs, faults, and other errors. When developing a system, it is important to ensure that it possesses fault tolerance. The specific level of performance is also developed for system’s reliability. The recoverability is the sub characteristic of reliability. This characteristic allows users to take corrective actions whenever an error occurs. The reliable system is one, which can quickly recover from a failure and resume working (Sauro & Kindlund, 2005). Reliability is viewed as an important quality attribute, which appears in all quality models. The users want a system that they can rely. The reliability can be defined as the capability of a system to maintain a specific performance level. The sub characteristics of reliability include maturity, fault tolerance, recoverability, and reliability conformance. Maturity of an ISO 9126 system can be comprehended as its capability to avoid failures. The fault tolerance of a system is the capability of a system to deliver specified performance (Phang, Kankanhalli &